Trial Design |
A prospective, observational, multi-centre blinded accuracy study of a novel diagnostic.
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Study Aim |
To assess the diagnostic accuracy of the Randox point of care (POC) multiplex polymerase chain reaction (Multiplex PCR) test in critically ill patients with suspected sepsis.
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The primary objective of this study is measurement of the sensitivity, specificity, positive predictive value and negative predictive value of this novel test, in comparison with conventional culture, in critically ill adults with suspected sepsis.
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“The secondary objectives of this study are:
(i) to estimate the true cost per test for conventional blood culture and for multiplex PCR
(ii) to estimate the time to result for conventional blood culture and for multiplex PCR”
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