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Trial Acronym TEST-IT
Clinical Area Critical Care
Trial Title Point Of Care Testing For Sepsis: A Diagnostic Accuracy Study
Trial Status Analysis and Reporting
Trial Registration

  • Recruitment
    Recruitment Target 4501
    Date Open to Recruitment October 2016
    Recruitment 412
    Date Closed to Recruitment February 2018
  • Trial Design
    Trial Design A prospective, observational, multi-centre blinded accuracy study of a novel diagnostic.
    Study Aim To assess the diagnostic accuracy of the Randox point of care (POC) multiplex polymerase chain reaction (Multiplex PCR) test in critically ill patients with suspected sepsis.
    The primary objective of this study is measurement of the sensitivity, specificity, positive predictive value and negative predictive value of this novel test, in comparison with conventional culture, in critically ill adults with suspected sepsis.
    “The secondary objectives of this study are:
    (i) to estimate the true cost per test for conventional blood culture and for multiplex PCR
    (ii) to estimate the time to result for conventional blood culture and for multiplex PCR”
  • Chief Investigator
    Chief Investigator Dr Ronan McMullan, Belfast Health & Social Care Trust

    Prof Danny McAuley, Queen’s University Belfast

  • Sponsor & Funders
    Sponsors Belfast Health and Social Care Trust
    Funder Innovate UK

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