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Trial Acronym PHIND
Clinical Area Critical Care
Trial Title Clinical Evaluation of a Point of Care (POC) assay to identify PHenotypes IN the Acute Respiratory Distress Syndrome
Status Analysis & Reporting
Trial Registration

  • Recruitment
    Recruitment Target 515
    Date Open to Recruitment
    Recruitment 520
    Date Closed to Recruitment September 2023


  • Trial Design
    Trial Design A multi-centre, prospective, observational study
    Study Aim The purpose of this project is to prospectively define hyper- and hypo-inflammatory phenotypes in patients with ARDS and determine clinical outcomes associated with each phenotype.
    Objective 1: Assess the clinical outcomes in patients with ARDS according to their prospectively defined inflammatory phenotype determined using a POC assay.
    Objective 2: (i) Assess the agreement of the phenotype allocation using a POC assay and the clinical study dataset
    (ii) Assess the stability of phenotype allocation over time
    (iii) Feasibility of delivering a POC assay in the NHS intensive care setting
  • Chief Investigator
    Chief Investigator Professor Danny McAuley, Queen’s University Belfast

  • Sponsor & Funder
    Sponsor Queen’s University Belfast
    Funder Innovate UK


    Queen’s University Belfast

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