REVIVE

Trial Acronym	REVIVE
Clinical Area	Critical Care
Description	Effectiveness of a programme of exercise on physical function in survivors of critical illness following discharge from the Intensive Care Unit (ICU): a randomised controlled trial.
Status	Closed

RECRUITMENT

Date Opened to Recruitment	January 2012
Target Recruitment	68
Recruitment to date	60
Date Opened to Recruitment	February 2015

TRIAL DESIGN

Trial Design	A prospective phase II randomised controlled clinical trial of exercise versus standard care following critical illness.
Study Aim	To investigate whether a 6 week exercise programme improves physical function in patients discharged from hospital following critical illness compared to standard care.
	Objective 1: To investigate whether a 6 week exercise programme improves physical function, quality of life, exercise capacity, anxiety and depression and self efficacy to exercise in patients discharged from hospital following critical illness.
	Objective 2: To determine the feasibility (safety, practicality and acceptability) of providing a 6 week exercise programme for patients discharged from hospital following critical illness.
	Objective 3: To explore patients’ perceptions of the benefits of the 6 week exercise programme.
	Objective 4: To examine medium term (6 months) effects of the exercise programme.
	Objective 5: To evaluate the cost-effectiveness of the exercise programme.

CHIEF INVESTIGATOR (CI)

Chief Investigator

Brenda O’Neill

SPONSOR(s) & FUNDER(s)

Sponsor	University of Ulster
Funder	Revive – Charity For The Regional Intensive Care Unit, Royal Hospitals

REGISTRATION

NCT01463579

https://clinicaltrials.gov/ct2/show/NCT01463579