Trial Acronym MIRROR
Clinical Area Ophthalmology
Description Efficacy of the Telescopic Mirror Implant for Age-related Macular Degeneration: The MIRROR Trial (acronym MIRROR). A Multicentre Randomised Controlled Clinical Trial
Status Closed
Date Opened to Recruitment 23rd May 2017
Target Recruitment 132
Recruitment to date
Date Closed to Recruitment N/A
No. of Sites 10
Trial Design Interventional multicentre randomised controlled trial.
Study Aim The main goal of the study is to investigate the effectiveness, safety, and mechanisms of action of a novel implantable intraocular telescopic device in advanced AMD. We will also conduct a cost-effectiveness analysis.

The specific objectives are to compare the effect of the telescopic implant at 12 months in terms of: Best corrected distance visual acuity; Other measures of visual function such as near acuity, reading speed and contrast sensitivity; Health-related and visual-related quality of life; Safety; Costs and cost-effectiveness; To explore whether patient ocular parameters such as scar size, and volume at site are associated with visual outcome; To assess the importance of Preferred Retinal Locus (PRL) and ocular dominance on outcomes; To evaluate the role of binocularity and visual summation on outcomes
Chief Investigator Miss Giuliana Silvestri
Sponsors Belfast Health and Social Care Trust
Funder NIHR Efficacy and Mechanism Evaluation (EME 13/160/03)
Links http://www.hra.nhs.uk/news/research-summaries/mirror-trial-version-1-0/