|Clinical Area||Paediatric Critical Care|
|Description||Sedation AND Weaning In CHildren|
|Status||Analysis & Reporting|
|Date Opened to Recruitment||February 2018 – October 2019|
|Recruitment to date||over 10,400 as of 14/10/2019|
|Date Closed to Recruitment||14/10/2019|
|No. of Sites||17|
|Trial Design||Prospective, cluster-randomised stepped wedge (SW) multi-centre clinical and cost-effectiveness trial with an internal pilot and a process evaluation.|
|Study Aim||The aim of this study is to determine if a protocol-based intervention for the management of children in intensive care units can reduce the duration of invasive mechanical ventilation (IMV). The study involves co-ordinated care and greater nursing involvement in the sedation and ventilator weaning of children. It will also assess cost effectiveness compared with usual care.
Alongside the trial a process evaluation will be conducted using the principles of the Medical Research Council (MRC).
|Chief Investigator||Professor Bronagh Blackwood|
|Sponsors||Queen’s University Belfast|
|Funder||NIHR Health Technology Assessment Programme (HTA)|